A Relative Of Lychee – Soursop
Nov 12, 2025
*Annona squamosa*, commonly known as spiny custard apple, is an evergreen tree belonging to the genus *Annona* in the family Annonaceae. It can reach up to 10 meters in height; its leaves are papery, obovate-oblong or elliptical, slightly convex on both sides, and anastomosing near the leaf margin; the flower buds are ovoid, the flowers are pale yellow, and the inner base has small red bumps; the fruit is nearly spherical or ovoid; the seeds are numerous and kidney-shaped; flowering occurs from April to July; fruiting from July to December.
*Annona squamosa* is native to tropical America and is distributed in Taiwan, Guangdong, Guangxi, and other parts of China, as well as subtropical regions. It prefers warm, humid, and sunny environments, is not cold-hardy, and is not particular about soil type. It thrives in deep, fertile, well-drained sandy soil. Common propagation methods include seed propagation and asexual reproduction.

Strangely, online information about its medicinal value far outweighs its "tasty" qualities. All parts of the soursop, including its leaves, roots, fruit, and seeds, have medicinal value. Although it has been used for treatment for a long time, scientists only began to seriously study the relationship between this fruit and cancer treatment in the late 20th century. The leaves and trunk of the soursop are primarily used to treat cancer. Hexanoic acid and other plant compounds isolated from this plant are the main active ingredients in fighting malignant cells.
The remarkable effects of soursop attracted the attention of several American scientists in 1970. Scientists conducted more than 20 studies on soursop. The results showed that extracts from soursop can effectively fight malignant cells in 12 types of cancer, including colon cancer, breast cancer, prostate cancer, lung cancer, and pancreatic cancer. At the same time, soursop also has antifungal and antiparasitic effects. In addition, it can help regulate blood pressure and is also an antidepressant and broad-spectrum antibiotic. Researchers claim that soursop could revolutionize the medical field, especially in the treatment of cancer.

Soursop (Cornfruit) has antioxidant, immune-boosting, digestive-promoting, and blood sugar-regulating effects, and moderate consumption can help improve health.
1. Antioxidant: Soursop is rich in vitamin C and polyphenols, which can eliminate free radicals in the body and delay oxidative damage to cells.
2. Boosts Immunity: Its vitamin C and trace elements such as zinc can stimulate the activity of immune cells, helping to enhance the body's disease resistance.
3. Promotes Digestion: The dietary fiber in the fruit can accelerate gastrointestinal motility, improve constipation symptoms, and maintain the balance of intestinal flora.
4. Regulates Blood Sugar: Its low glycemic index and the synergistic effect of chromium help stabilize postprandial blood sugar fluctuations.
It is recommended to consume no more than 200 grams per day, avoid eating on an empty stomach, and diabetic patients should control their intake under the guidance of a nutritionist.

Soursop extract is derived from the tropical plant Annona muricata (commonly known as red durian). Although this plant has "durian" in its name, it does not have a foul odor. Depending on the part used (fruit, leaves, roots, seeds) and the processing method, its extract has diverse biological activities and uses.
| Extraction site | Main active ingredients/uses | Related |
| Leaves/fruits | Polyphenols | Studies have shown that its polyphenols have the ability to scavenge DPPH free radicals and hydroxyl free radicals. |
| Dietary supplements | As a dietary supplement, it is often used to support the body's health. | |
| surface active ingredients | It is used as a conditioning agent in personal care products and has antioxidant and antibacterial properties. | |
| Root | Blood sugar lowering ingredients | Studies have shown that it has a significant effect in lowering blood sugar and reducing glycated hemoglobin. |
| Seed | Sophora flavescens, etc. | Its mechanism of action is related to changes in mitochondrial membrane potential; it regulates the activity of γ-aminobutyric acid receptors; its free radical scavenging effect is superior to that of vitamin C, thus delaying the oxidative aging process of brain cells. |
| Whole fruit/Pulp | Used in fragrance preparation | It can be made into flavorings for use in the food and other industries. The pulp can be eaten directly; it is sweet, sour, and juicy. |
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