Product Introduction
Cholestyramine is a styrene type strongly basic quaternary amine anion exchange resin. Molecular weight over 1 million. Insoluble in water, its chloride is commonly used. It is not absorbed by oral administration, and is combined with bile acid by ion exchange in the intestine, preventing the absorption of bile acid and cholesterol, and promoting the excretion of the two. Under the action of cholestyramine, the intestinal and hepatic circulation of bile acid is terminated, and the content of bile acid in the blood and liver decreases, which promotes the decomposition of delipoprotein and cholesterol in the liver, resulting in a decrease in the level of cholesterol in the liver and blood.
It is mainly used for type Ⅱa (high cholesterol type), which can significantly reduce the low-density lipoprotein (LDL) in the blood, and reduce the LDL of type Ⅱb, but can cause a slight increase in very low-density lipoprotein (VLDL). The general dosage has no good effect on type Ⅲ and Ⅳ hyperlipidemia. Each time 4 ~ 5g, 3 times a day.
Cholestyramine is a relatively safe drug among the existing hypolipidemic drugs. Because it is not absorbed by the gastrointestinal tract, it has no systemic side effects. However, patients are not willing to accept it due to the large dose. The main side effects are nausea, abdominal distension, fecal secretion or diarrhea, and the symptoms can disappear on their own if the medication is continued.
Product Specification
Product Name: | cholestyramine powder | Assay: | 99% |
Other Name: | cholestyramine | Appearance: | White powder |
Latin Name: | / | Active Ingredient: | cholestyramine |
Extract Part: | / | Grade: | Food Grade |
Extraction Type: | / | Packing: | 25kg/drum |
1. Product Function & Application
Function
Drugs with powerful cholesterol lowering effect. It belongs to a high molecular weight quaternary acrylamine cation exchange epoxy resin. After oral administration, it fuses with intestinal bile acid to block the catabolism of bile acid, so that the secretion of bile acid is increased by 3 to 15 times compared with normal, the bile acid in the liver is reduced, and 7-a hydroxylase (speed) in the liver microparticles. Restriction enzymes) are activated and promote the conversion of cholesterol to bile acid. In addition, because bile acid is an essential substance for gastrointestinal digestion and absorption of cholesterol, after the drug is fused with intestinal bile acid, the amount of bile acid in the intestine is reduced, so the digestion and absorption of cholesterol in food materials is reduced, resulting in blood cholesterol and Low density protein decreases. The key is type Ia hyperproteinuria characterized by high density, low lipoprotein and high protein. For type Ib hyperproteinuria, it is necessary to use drugs that can significantly reduce blood triglycerides, such as clotamine or vitamin b3. In addition, the drug can also be used for severe itching of the skin caused by incomplete obstructive jaundice, and has an antipruritic effect.
Scope of application
For type Ⅱa hyperlipidemia, hypercholesteroluria. This product reduces blood total cholesterol and low-density protein concentrations, and has no effect on blood cell triglyceride concentrations or slightly increases them. Therefore, it is ineffective for those with simple triglyceride increases. This product can also be used for itching caused by incomplete blockage of the common bile duct, and for diarrhea caused by excessive gastrointestinal bile acid in patients with ileal disease.
Halal, Kosher,ISO 9001 Certificate are our strong backing to ensure the quality of our product.
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1. Deliver & Shipping
We accept International Express--Fedex/DHL/UPS, air shipping and sea shipping
Cargo weight | Packing | Shipping method | Lead-time |
5-50kg | Below 5kg Use Foil bag;5-25kg use two layer PP bag,then into master carton or cardboard drum | International express | 7-10days |
100-200kg | 25kg/drum,use two layer PP bag,then into cardboard drum | Air shipping | 7-10days |
Over 500kg | 25kg/drum,use two layer PP bag,then into cardboard drum | Sea shipping | 20-45days |
2. FAQ
1. Can I get some free sample of you herb extract?
Yes, we offer free sample to client but the shipping cost will be paid by client.
2. How to make payment and what is the payment term? Payment can be done by T/T, Credit Card, Western Union, PayPal and more.
3. How does your factory make sure the product quality?
First of all, we have about 10years experience in plant extract field, we already have a mature quality control procedure. Also we will final check before shipping to avoid any problem.
4. Can you do OEM for me?
We accept OEM orders, just contact us and send us your request. We will offer you a reasonable price and make samples ASAP.
5. How to get in touch with us? You can chat with us by email, Skype and Whats-App or simply drop us an email, a phone call. All our contacts are shown in website.
