Cycloastragenol Powder

Cycloastragenol Powder

Product name:cycloastragenol powder
Appearance:White powder
Active ingredient:cycloastragenol
Country of origin: China
Grade: Food grade
Certificate:Halal/Kosher/ISO9001/GMO free
Customization: Yes
Application field: Medical,health care,food
Stock:Yes
Output:50 tons/month
Order lead time:7-15days
Payment method: T/T, paypal, western union
MOQ:2KG
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Description
Technical Parameters

Product Introduction

Astragalus is one of the commonly used Chinese herbal medicines. When used raw, it can help to strengthen the surface, diuretic and reduce swelling, and support toxins and promote muscle; Studies have shown that astragalus and its saponins have significant immune regulation, anti-inflammatory, antioxidant, anti-ischemic brain injury, anti-aging and nootropic effects. Astragalus saponins have been studied in depth at home and abroad, and dozens of astragalus saponins have been isolated and identified, such as acetyl astragaloside I, astragaloside I, II, astragaloside I-VIII, etc., astragaloside B, astragalus saponin I-XVI . Astragaloeide IV, also known as astragaloside IV, is an important saponin compound isolated from Astragalus with various pharmacological activities. It has a wide range of biological activities in the treatment of cardiovascular and cerebrovascular diseases, anti-aging, anti-inflammatory, analgesic, and immune regulation. However, the relative bioavailability of astragaloside in vivo is insufficient due to its relatively large molecular mass and inert solubility, which limits the development and promotion of its Chemicalbook as a drug. Astragaloside IV is a representative saponin component of traditional Chinese medicine Astragalus, and cycloastragenol is the sapogenin of astragaloside IV. Cycloastragaloside is the main hydrolyzed metabolite of astragaloside IV in the intestinal tract and absorbed into the blood component. It has a relatively small molecular mass and strong lipophilicity, which is conducive to biofilm penetration and gastrointestinal absorption to achieve better performance. bioavailability. A large number of modern medical studies have proved that astragaloside IV can reduce ischemia-reperfusion brain tissue damage by enhancing the body's ability to scavenge oxygen free radicals, inhibiting peroxidation, and reducing neuronal calcium overload. The research of Geron Biotechnology Company of the United States found that CAG has a significant telomerase activation effect. RevGenetics of the United States also confirmed through research that CAG is one of the raw materials of functional cosmetics and nutritional foods, and is currently the only one that can be used in The raw material for activating telomerase in human cells is a promising anti-aging substance.

Product Specification

Product Name:

cycloastragenol powder

Assay:

98%

Other Name:

cycloastragenol

Appearance:

White powder

Latin Name:

/

Active Ingredient:

cycloastragenol

Extract Part:

/

Grade:

Food Grade

Extraction Type:

/

Packing:

2kg/drum

1. Product Function & Application

Function

As a secondary metabolite with great medicinal value in Astragalus, cycloastragalus has protective effects on cardiovascular disease, stroke, fatty liver, abdominal aortic aneurysm and other diseases, and can activate telomerase and regulate immunity. , to promote wound healing and hair growth, etc. However, there are still some problems in the current research on the pharmacological effects of cycloastragalin:

1. Relevant in vitro experiments found that cycloastragalus has cytotoxicity at a certain concentration, suggesting that cycloastragalus is not absolutely safe, and its toxicity to cells needs further research, and its safety in animals needs to be further verified;

2. The research on cycloastragalus is mostly limited to the activation target of telomerase. Although it has advantages in the development of related health care products, it limits its deeper and wider research to a certain extent. Although cyclic astragalus has been shown to inhibit the adenylate-activated protein kinase (AMPK) pathway, the farnesoid X receptor (FXR) transcription factor and silent mating type information regulator (silent mating type information regulation) SIRT1) protein regulation has made some supplements for its pharmacological targets, but there is still a lack of related pharmacological activities and mechanisms of action. Although there are still some problems in the research on the pharmacological effects of cycloastragalus, it is undeniable that its In the future, it is necessary to further strengthen the research on its protective effect on diseases such as cardiac fibrosis, congestive heart failure and arrhythmia, as well as theoretical and experimental research on improving cardiovascular disease risk indicators and regulating endothelial cell homeostasis. It can be better used in clinical practice. At the same time, the potential of cycloastragalus in the treatment of cerebral ischemia and mental diseases should be fully exploited, and its effect on cerebral neurovascular diseases should be regarded as a new direction for future research.

Application

It has enhanced immune function, liver protection, diuresis, anti-aging, anti-stress, antihypertensive and broader antibacterial effects, and can inhibit virus reproduction and tumor growth. Can improve cardiopulmonary function, strengthen cardiac contractility, dilate blood vessels, improve skin blood circulation and nutritional status. Astragalus also induces interferon and mobilizes the immune function of the body. Increase energy, anti-fatigue, make mutations, inhibit the role of osteoclasts.


Product Qualification

Inspection Item

Specification

Result

Test Method

Appearance

Brown Powder

Qualified

Visual

Odor

Characteristic

Qualified

Organoleptic

Identity

TLC

Qualified

TLC

HPLC

Qualified

HPLC


Cycloastragenol

NLT 98.00%

98.12%

HPLC-RID

Loss on Drying

NMT 5.00%

0.57%

USP43-NF38<731>

Residue on Ignition

NMT 5.00%

0.93%

USP43-NF38<281>

Arsenic(MDL0.05)

NMT 1.50ppm

0.25

ICP-MS

Lead(MDL0.02)

NMT 5.00ppm

0.19

ICP-MS

Cadmium(MDL0.02)

NMT 0.30ppm

ND

ICP-MS

Mercury(MDL0.005)

NMT 0.10ppm

ND

ICP-MS

Total Plate Count

NMT 10000cfu/g

480

USP43-NF38<2021>

Molds and Yeasts

NMT 1000cfu/g

50

USP43-NF38<2021>

E.Coli

Absent/10g

Absent

USP43-NF38<2022>

Salmonella

Absent/25g

Absent

USP43-NF38<2022>

Packaging and Storage

Packing in paper-drums and two sealed plastic-bags inside

Store at room temperature,protected from light and moisture



Halal, Kosher,ISO 9001 Certificate are our strong backing to ensure the quality of our product.

certificate

Deliver & Shipping

We accept International Express--Fedex/DHL/UPS, air shipping and sea shipping

Cargo weight

Packing

Shipping method

Lead-time

5-50kg

Below 5kg Use Foil bag;5-25kg use two layer PP bag,then into master carton or cardboard drum

International express

7-10days

100-200kg

25kg/drum,use two layer PP bag,then into cardboard drum

Air shipping

7-10days

Over 500kg

25kg/drum,use two layer PP bag,then into cardboard drum

Sea shipping

20-45days


FAQ

1. Can I get some free sample of you herb extract?

Yes, we offer free sample to client but the shipping cost will be paid by client.

2. How to make payment and what is the payment term? Payment can be done by T/T, Credit Card, Western Union, PayPal and more.

3. How does your factory make sure the product quality?

First of all, we have about 10years experience in plant extract field, we already have a mature quality control procedure. Also we will final check before shipping to avoid any problem.

4. Can you do OEM for me?

We accept OEM orders, just contact us and send us your request. We will offer you a reasonable price and make samples ASAP.

5. How to get in touch with us? You can chat with us by email, Skype and Whats-App or simply drop us an email, a phone call. All our contacts are shown in website.


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