Product Introduction
Bladderwrack powder, has anti-inflammatory effect Bladderwrack has obvious inhibitory effect on inflammatory exudation and tissue edema caused by various pro-inflammatory agents. Antibacterial effect The decanoylacetaldehyde in Bladderwrack is an active antibacterial ingredient, and has obvious inhibitory effect on Cataractococcus, Hemolytic Streptococcus, Influenza Bacillus, Streptococcus pneumoniae and Staphylococcus aureus.
1. Enhance immunity
Enhance the phagocytic ability of WBC and improve serum properdin. In the treatment of chronic bronchitis, synthetic houttuyniacin can significantly improve the phagocytic ability of WBC to Staphylococcus albicans, and serum properdin is significantly increased. Rabbits were injected intramuscularly with 8 mg of houttuynia per day. After continuous administration for 3 days, properdin in serum also increased significantly. Houttuynia cordata improves the immunity of the body, which is of great significance to the treatment of infectious venereal diseases.
2. Antibacterial effect
A yellow oily substance extracted from Houttuynia cordata has an inhibitory effect on various microorganisms (especially yeast and mold), and has an inhibitory effect on hemolytic streptococcus, staphylococcus aureus, influenza bacillus, catarella, pneumococcus significant inhibitory effect. It also has an effect on Escherichia coli, Shigella, and Salmonella typhi. The artificially synthesized decanoylacetaldehyde sodium bisulfite adduct is called synthetic houttuyniacin. The synthetic sodium dodecanoylacetaldehyde sodium bisulfite adduct is called neochromatin, which has obvious inhibitory effects on various bacteria in vitro and in vivo experiments: MIC for Staphylococcus aureus and penicillin resistance is 62.5 ~ 80mcg /ml, 1.25mg/ml for influenza bacillus. 16mcg/ml for Mycobacterium tuberculosis H37RY strain on Purbai's liquid medium. In the modified Sutong's semi-solid medium, it is 25mcg/ml, and its potassium salt is 12.5mcg/ml. The synthetic houttuyniacin isoniazid has a strong effect on TB bacilli, and its MIC is 0.78～3.1mcg/ml, which is suitable for mice infected with TB. It can significantly prolong the survival time. Intraperitoneal injection of 1 mg per mouse can prolong the survival period of mice by 62 days, and the effect of mixed food feeding is better.
3. Virus action
Houttuynia cordata is used for tissue culture of human embryonic kidney primary monolayer epithelial cells. Houttuynia cordata decoction (1:10) has an inhibitory effect on influenza Asia A Jingke 68-1 strain, and can delay the growth of orphan virus ECHO11. Zhu Yutong reported that several non-volatile oil fractions were obtained by extraction with ethanol. Among them, houttuyniacin Ⅲ has preventive protective effect on influenza virus-infected mice, but has no obvious effect on EMC and HSVⅡ. Houttuynia cordata extract (4g crude drug/ml) has obvious preventive and protective effect on mice infected with reinfluenza virus. However, there is no obvious protective effect on encephalomyocarditis virus and herpes virus type Ⅱ infection. And it is proved that the anti-influenza virus component of Houttuynia cordata is not in the volatile oil part, but in the non-volatile matter. In vitro experiments have shown that Houttuynia cordata water extract can inhibit HSV-1 and HSV-2 infection, and the specific mechanism is to inhibit the activity of transcription factors required for virus replication.
4. Diuretic effect
Perfusion of toad kidneys or frog webs with Houttuynia cordata can dilate capillaries, increase blood flow and urine secretion, and thus have a diuretic effect. Its effect may be caused by organic matter. Potassium only plays an additional role in increasing diuresis. When it acts directly, it can weaken the activity of leptospira - die - lyse, and can also delay the onset of guinea pigs artificially infected with leptospirosis.
5. Compatibility with TMP
In the study of compatibility with TMP, Zhang Yongheng reported that there was a very significant difference between the 0.75mg/ml Houttuynia cordata group and the 0.75mg/ml Houttuynia cordata-7.5mg/ml TMP compatibility group (t=5.6) P<0.001. sex. Compared with the 7.5mg/ml TMP group (t=2.78), P<0.01, the difference was significant. It shows that the antibacterial effect of the two is better than the single use, and the two have a synergistic effect. 0.1ml/ml Houttuynia cordata volatile oil has no antibacterial effect, 0.1ml/ml Houttuynia cordata volatile oil-7.5mg/mlTMP compatibility group and 7.5mg/mlTMP group (t=4.2) P<0.001, there is a very significant antagonistic effect , indicating that Houttuynia cordata volatile oil can reduce the antibacterial effect of TMP. But there are exceptions. The combination of the two can enhance the effect of anti-paratyphoid and Shigella sonnei. Therefore, while affirming the antagonistic effect, the synergistic effect on individual strains should not be ignored.
6. The role of pathogenic microorganisms
The fresh juice of Houttuynia cordata has inhibitory effect on Staphylococcus aureus, and the effect is weakened after heating. In vitro tests have proved that Houttuynia cordata decoction is effective against a variety of gram-positive and negative bacteria such as Staphylococcus aureus, Staphylococcus albicans, hemolytic streptococcus, pneumococcus, catarella, diphtheria, proteus, Shiga , Shi Shi, Fu Shi and Songnei Shigella, Enteritidis, etc. have varying degrees of inhibition. The ether extract of Houttuynia cordata has obvious inhibitory effect on Mycobacterium tuberculosis in vitro. An oily substance extracted from Houttuynia cordata has inhibitory effects on various microorganisms (especially mold and yeast), and has obvious effects on hemolytic streptococcus, staphylococcus aureus, influenza bacillus, catarella, and pneumococcus Inhibitory effect; also has inhibitory effect on Escherichia coli, Shigella, and Typhi. But there are also reports that the antibacterial effect of Houttuynia cordata decoction is not obvious.
The main antibacterial active ingredient of Houttuynia cordata has obvious antibacterial effect on a variety of bacteria, acid-fast bacilli and fungi, but the compound is unstable. Its sodium bisulfite adduct is stable and retains its antibacterial activity. The sodium bisulfite adduct of decanoylacetaldehyde synthesized in China is called synthetic houttuyniacin, which has obvious bacteriostatic effect on a variety of gram-positive and negative bacteria in vitro. Staphylococcus aureus and its Penicillin-resistant strains, Streptococcus pneumoniae, Streptococcus A, and Bacillus influenzae were more sensitive, followed by Cataractococcus and Bacillus typhi, while Escherichia coli, Pseudomonas aeruginosa and Shigella dysenteriae were less sensitive. For tuberculosis infection in mice, houttuyniacin can significantly prolong the survival time. In addition, it also has obvious inhibitory effects on Candida albicans, Cryptococcus neoformans, Sporothrix, Aspergillus, Chromophytes, rubrum rubrum, imbricum dermatophytes, Microsporum gypseum, Microsporum rust, and Sharkiaphytes, etc. effect. The artificially synthesized dodecanoylacetaldehyde sodium hydrogen sulfite adduct is called new houttuyniacin, which also has inhibitory effects on pneumococcus, typhoid bacillus, staphylococcus aureus, Escherichia coli and sporothrix in vitro. The houttuyniacin isoniazon of synthetic Kun has a strong inhibitory effect on Mycobacterium tuberculosis in vitro and in vivo.
Houttuynia cordata decoction has a strong inhibitory effect on Leptospira in test tube. When directly acting, the activity of Leptospira can be weakened-death-lysed, and the onset period of guinea pigs artificially infected with Leptospira can be delayed.
Houttuynia cordata decoction (1:10) has inhibitory effect on influenza Asian A Jingke 68-1 strain, and can delay the growth of orphan virus (ECHO11) using human embryonic kidney primary monolayer epithelial cell tissue culture. Experiments show that the anti-influenza virus components of Houttuynia cordata are in non-volatile matter. Houttuynia cordata extract has obvious preventive and protective effect on influenza virus-infected mice, and both gavage and intranasal administration have obvious effects; but it has no obvious protective effect on encephalomyocarditis virus and herpes virus type Ⅱ infection.
7. Effects on the immune system
Houttuynia cordata decoction can significantly promote the ability of human peripheral blood leukocytes to phagocytose Staphylococcus aureus in vitro. Synthetic houttuyniacin can improve the phagocytic function of leukocytes in patients with chronic bronchitis, and increase the serum properdin level in rabbits and patients.
8. Anti-tumor effect
The inhibitory effect of new houttuyniacin on Ehrlich ascites carcinoma may be related to the increase of cAMP level in cancer cells. Experiments showed that the total number of cancer cells, the division index of cancer cells, and the volume of ascites were significantly reduced when mice were injected with different doses of new houttuynia at different times, while the level of cAMP in cancer cells was increased.
9. Anti-inflammatory effect
Houttuynia cordata decoction has a significant anti-inflammatory effect on formaldehyde-induced swollen feet in rats, and can also significantly inhibit the thermal denaturation of human γ-globulin in the presence of Cu++; Mouse ear swelling and increased skin capillary permeability also significantly inhibited HCA-induced peritoneal capillary dye exudation. The flavonoids such as quercetin, quercitrin and isoquercitrin contained in Houttuynia cordata also have significant anti-inflammatory effects, which can significantly inhibit the hypercapillary hyperactivity in the early stage of inflammation.
Product Specification
Product Name: | Bladderwrack powder | Assay: | 10:1,5%,10% |
Other Name: | Bladderwrack extract | Appearance: | Brown Fine Powder |
Latin Name: | Houttuynia cordata Thunb. | Active Ingredient: | Bladderwrack extract |
Extract Part: | stem | Grade: | Food Grade |
Extraction Type: | Solvent Extraction | Packing: | 25kg/drum |
Product Function & Application
1. Anti-inflammatory effect Houttuynia cordata has obvious inhibitory effect on inflammatory exudation and tissue edema caused by various pro-inflammatory agents.
2. Antibacterial effect The decanoyl acetaldehyde in Houttuynia cordata is an effective antibacterial ingredient, which has obvious inhibitory effect on cataractococcus, hemolytic streptococcus, influenza bacillus, pneumococcus and staphylococcus aureus, and has obvious inhibitory effect on Escherichia coli, Shigella, Salmonella typhi and Sporothrix also have inhibitory effects. In vitro experiments show that fresh Houttuynia cordata extract has anti-Staphylococcus aureus effect in vitro, the minimum inhibitory concentration (MIC) is 1.2mg/mL, and the minimum bactericidal concentration (MBC) is 5.0mg/mL.
3. Enhance the immune function of Houttuynia cordata decoction and decanoylacetaldehyde (houttuyniacin) can enhance the phagocytic function of leukocytes.
4. Antipyretic effect Houttuynia cordata injection has obvious antipyretic effect.
5. Antiviral effect The active ingredient of Houttuynia cordata's antiviral effect is its volatile oil, and its mechanism of action is to kill influenza virus by interfering with the virus envelope. Houttuynia cordata can protect host cells and inhibit apoptosis caused by viral infection.
6. Anti-allergic and antitussive effect
Halal, Kosher,ISO 9001 Certificate are our strong backing to ensure the quality of our product.
1. Why choose us?
Xi'an Haoze Biotechnology Co., Ltd was established in 2015, and located in Hi-Tech Industrial Zone in Xi'an Shaanxi province China, the main Bladderwrack powder supplier in Chinese mainland .
Our main customer are Manufacturer, wholesaler, exporter, retailer.
Main market are North American, European, South Asia,Australia and Africa.
Our company is supported by three plant extract processing and production bases, the annual supply capacity reaches 500 tons of plant extracts 1000 tons of fruit and vegetable extract and 500 tons of powdered raw materials.
Also we have a professional and experienced sales and service team. They will follow up each project from the beginning until finished and after sale service.
